Membrane Technology and Application of Glass Bottle Butyl Rubber Plug

Although the internal cleanliness,chemical stability,airtightness,and biological performance of butyl rubber stoppers are all good,due to the complexity of the formula and the concentration gradient of the raw materials added,they are encapsulated by drugs that have strong activity against some molecules.Drug absorption,adsorption,leaching,and penetration have produced problems with the compatibility of rubber stoppers and drugs.Some of the more prominent are cephalosporins,some large infusions,and more traditional Chinese medicine injection preparations.Therefore,through the use of an inert soft coating covering the surface of the rubber plug to isolate the direct contact between the drug and the rubber stopper,the compatibility with the drug can be significantly improved.
Today,all kinds of suitable membrane materials used in butyl rubber stoppers are taken by the technicians of domestic and foreign butyl rubber stopper manufacturers.

This articlemakes a simple statement on the status quo and development trend of the butyl rubber plug's membrane technology for your colleagues to read,and hopes to inspire you.

one.Butyl rubber plug membrane technology

Due to its many advantages,the butyl rubber plug coating can effectively reduce the absorption,adsorption,leaching and infiltration between the rubber plug and the drug,and improve the long-term stability of the drug;for example,by forming a film on the surface of the rubber plug.The mechanical lubricity of the rubber plug greatly reduces the increase in the amount of insoluble particles in the liquid due to the silicone oil.